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DeCS
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Descriptor English:
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Antibody-Dependent Cell Cytotoxicity
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Descriptor Spanish:
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Citotoxicidad Celular Anticuerpo-Dependiente
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Descriptor Portuguese:
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Citotoxicidade Celular Anticorpo-Dependente
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Synonyms English:
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Cytotoxicity, Antibody-Dependent Cell
ADCC
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Tree Number:
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G04.610.270.070
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Definition English:
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The phenomenon of antibody-mediated target cell destruction by non-sensitized effector cells. The identity of the target cell varies, but it must possess surface IMMUNOGLOBULIN G whose Fc portion is intact. The effector cell is a "killer" cell possessing Fc receptors. It may be a lymphocyte lacking conventional B- or T-cell markers, or a monocyte, macrophage, or polynuclear leukocyte, depending on the identity of the target cell. The reaction is complement-independent. |
Indexing Annotation English:
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DF: note short X ref
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History Note English:
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78
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Allowable Qualifiers English:
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Record Number:
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925
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Unique Identifier:
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D000920
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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